A novel cancer-associated cassette exon in TLN1 alters Talin 1 mechanosensitivity
L. M. Gallego-Paez, W. J. S. Edwards, Y. Guo, M. Chanduri, T. Koorman, C.-Y. Lee, N. Grexa, P. W. B. Derksen, J. Yan, M. A. Schwartz, J. Mauer, B. T. Goult
The paper identifies a cancer-associated exon in TLN1 that alters mechanosensitivity by affecting R1-R2 switch dynamics and vinculin binding.
Journal of Cell Biology · Mar 6, 2023Peer-reviewedCancer Biology