Lung epithelial cell-derived C3 protects against pneumonia-induced lung injury
A. N. Ozanturk, S. K. Sahu, D. H. Kulkarni, L. Ma, R. A. Barve, J. McPhatter, L. Garnica, L. Dannull, X. Wu, S. L. Brody, J. P. Atkinson, H. S. Kulkarni
The paper shows lung-derived C3 reduces pneumonia-induced lung injury through the Factor B pathway, independent of circulating C3 levels.
bioRxiv · Feb 3, 2022Immunology