BiochemistrybioRxiv
Universal open MHC-I molecules for rapid peptide loading and enhanced complex stability across HLA allotypes
Y. Sun, M. C. Young, C. H. Woodward…·N. G. Sgourakis
This paper introduces engineered MHC-I molecules with enhanced stability and peptide exchange capabilities across multiple HLA allotypes, enabling improved antigen screening and TCR analysis.
DOI 10.1073/pnas.2304055120