A Newcastle disease virus (NDV) expressing membrane-anchored spike as a cost-effective inactivated SARS-CoV-2 vaccine
W. Sun, S. McCroskery, W.-C. Liu, S. R. Leist, Y. Liu, R. A. Albrecht, S. Slamanig, J. Oliva, F. Amanat, A. Schaefer, K. H. Dinnon, B. L. Innis, A. Garcia-Sastre, F. Krammer, R. S. Baric, P. Palese
This paper evaluates an inactivated Newcastle disease virus expressing the SARS-CoV-2 spike protein as a cost-effective vaccine, showing immunogenicity and protective efficacy in animal models.
bioRxiv · Jul 30, 2020Microbiology