ImmunologybioRxiv
Immune cells lacking Y chromosome have widespread dysregulation of autosomal genes
J. P. Dumanski, J. Halvardson, H. Davies…·L. A. Forsberg
The paper examines immune cells with mosaic loss of the Y chromosome, finding widespread dysregulation of autosomal genes and linking this to immune dysfunction and disease.
DOI 10.1007/s00018-021-03822-w