Author

J. Peschek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Assay:protein sequence· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Sil· 1 shared C. Rivera· 1 shared D. G. Ruiz· 1 shared D. Mullins· 1 shared J. Kopp· 1 shared J. L. Gerber· 1 shared K. Crotty· 1 shared L. Worf· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

A. Sil

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2 papers

Recent·Most cited

Structural and mechanistic insights into activation of the human RNA ligase RTCB by Archease

J. L. Gerber, S. I. M. Guzman, L. Worf, P. Hubbe, J. Kopp, J. Peschek

The paper reports structural and biochemical analysis of the human RTCB-Archease complex during RNA ligation, revealing the mechanism of GTP-dependent activation and substrate regulation.

bioRxiv · Mar 30, 2023Biochemistry

Protomer alignment modulates specificity of RNA substrate recognition by Ire1

W. Li, K. Crotty, D. G. Ruiz, M. Voorhies, C. Rivera, A. Sil, D. Mullins, M. Jacobson, J. Peschek, P. Walter

The paper shows that changing two amino acids in S. cerevisiae Ire1 to their S. pombe counterparts makes it promiscuous, revealing that protomer alignment modulates RNA substrate specificity.

eLife · Apr 27, 2021Peer-reviewedBiochemistry