Cleavage region organizes the structural architecture of the B2 SINE ribozyme
A. Singhal, T. Mrozowich, S. N. Chaudhury, C. Rivera, M. Badmalia, J. T. Lee, T. R. Patel, K. Sanbonmatsu
The paper determines the structural ensemble-to-function relations of the B2 SINE ribozyme using RNA chemical probing, X-ray scattering, and modeling, showing cleavage site dependency on its structure and function.
bioRxiv · Jul 22, 2024 · PreprintBiophysics