Author

J. Kopp

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Assay:structural biology· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1 Organism:E. coli· 1 Assay:flow cytometry· 1

Frequent Co-Authors

J. Peschek· 2 shared A. Gruenberger· 1 shared A. M. Y. Zhang· 1 shared A. Zicler· 1 shared B. Zacchetti· 1 shared C. H. Borchers· 1 shared C. Herwig· 1 shared C. Slouka· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBiochemistry

J. Peschek

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4 papers

Recent·Most cited

Structure of fungal tRNA ligase with RNA reveals conserved substrate binding principles

S. Koehler, J. Kopp, J. Peschek

The paper reports the crystal structure of fungal Trl1-LIG with a tRNA substrate, revealing conserved binding principles and RNA end specificity.

bioRxiv · Jun 6, 2024 · PreprintBiochemistry

Structural and mechanistic insights into activation of the human RNA ligase RTCB by Archease

J. L. Gerber, S. I. M. Guzman, L. Worf, P. Hubbe, J. Kopp, J. Peschek

The paper reports structural and biochemical analysis of the human RTCB-Archease complex during RNA ligation, revealing the mechanism of GTP-dependent activation and substrate regulation.

bioRxiv · Mar 30, 2023Biochemistry

Hyperinsulinemia acts via acinar insulin receptors to initiate pancreatic cancer by increasing digestive enzyme production and inflammation

A. M. Y. Zhang, Y. H. Xia, J. S. H. Lin, K. H. Chu, W. C. K. Wang, T. J. J. Ruiter, J. C. C. Yang, N. Chen, J. Chhuor, S. Patil, H. H. Cen, E. Rideout, V. R. Richard, D. F. Schaeffer, R. P. Zahedi, , J. Kopp

bioRxiv · May 6, 2022Cancer Biology

Reducing phenotypic instabilities of microbial population during continuous cultivation based on cell switching dynamics

T. M. Nguyen, S. Telek, A. Zicler, J. A. Martinez, B. Zacchetti, J. Kopp, C. Slouka, C. Herwig, A. Gruenberger, D. Frank

This paper demonstrates that allowing microbial cells to switch phenotypes around a threshold, rather than enforcing a fixed trajectory, leads to more stable population behavior during continuous cultivation.

bioRxiv · Jan 13, 2021Microbiology