Author

J. Pfeil

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Approach:benchmark study· 1 Assay:clinical cohort / trial· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. D. Sahu· 1 shared A. Hamann· 1 shared A. Hoffmann· 1 shared A. S. Halkola· 1 shared A.-K. Mueller· 1 shared B. G. Vincent· 1 shared B. von Thulen· 1 shared C. H. Wai· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCancer Biology

A. D. Sahu

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A Community Challenge to Predict Clinical Outcomes After Immune Checkpoint Blockade in Non-Small Cell Lung Cancer

M. Mason, O. Lapuente-Santana, A. S. Halkola, W. Wang, R. Mall, X. Xiao, J. Kaufman, J. Fu, J. Pfeil, J. Banerjee, V. Chung, H. Chang, S. D. Chasalow, H. Y. Lin, R. Chai, , B. G. Vincent

The paper evaluates predictive models for immune checkpoint inhibitor outcomes in NSCLC using clinical trial data from two RCTs, finding that models combining PD-L1, TMB, and immune signatures outperform single biomarkers.

Journal of Translational Medicine · Feb 21, 2024Peer-reviewedCancer Biology

Reversible brain edema in experimental cerebral malaria is associated with transcellular blood-brain barrier disruption and delayed microhemorrhages

A. Hoffmann, J. Jin, M. Aida, C. H. Wai, S. Mohanty, P. K. Sahu, R. Pattnaik, L. Pirpamer, M. Fischer, S. Heiland, M. Lanzer, F. Frischknecht, A.-K. Mueller, J. Pfeil, M. Majhi, , M. Bendszus

This study identifies transcellular blood-brain barrier disruption as a mechanism for reversible brain swelling in experimental cerebral malaria, with implications for therapeutic strategies.

bioRxiv · Nov 26, 2021 · PreprintNeuroscience

Prevention of EAE by PEGylated Antigenic Peptide

J. Pfeil, M. Simonetti, U. Lauer, B. von Thulen, P. Durek, C. Poulsen, J. Pawlowska, M. Kroger, R. Krahmer, F. Leenders, U. Hoffmann, A. Hamann

This study shows that PEGylated antigenic peptides can prevent EAE in mice by inducing regulatory T cells, but are ineffective when administered during peak disease.

bioRxiv · Sep 8, 2020Immunology