Author

J. R. Atack

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

B. D. Bax· 2 shared C. R. Koulouris· 1 shared G. D. Fenn· 1 shared H. Waller-Evans· 1 shared J. A. Gillespie· 1 shared K. T. Elvers· 1 shared O. Grubisha· 1 shared R. A. Nicholls· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiophysics

B. D. Bax

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintFeb 12, 2021

Tyrosine 121 moves revealing a druggable pocket that couples catalysis to ATP-binding in serine racemase

C. R. Koulouris, S. E. Gardiner, T. K. Harris…·B. D. Bax

The paper identifies a druggable pocket involving Tyr121 that couples catalysis to ATP-binding in serine racemase by analyzing structural changes in closed and open enzyme forms.

DOI 10.1101/2021.02.12.430960

humanstructural biology

𝕏 PostBluesky

Pharmacology & ToxicologybioRxivPreprintJul 8, 2020

Crystallization and structure of ebselen bound to cysteine 141 of human inositol monophosphatase (IMPase).

G. D. Fenn, H. Waller-Evans, J. R. Atack, B. D. Bax

The paper presents the 1.47 Å crystal structure of human IMPase bound to ebselen, showing covalent attachment to Cys141 and tetramer formation through dimer interactions.

DOI 10.1101/2020.07.08.193284

humanprotein structure

𝕏 PostBluesky