Author

K. T. Elvers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

B. D. Bax· 2 shared A. D. Davidson· 1 shared A. P. Beltrami· 1 shared C. R. Koulouris· 1 shared D. Arnold· 1 shared D. Hill· 1 shared E. Avolio· 1 shared F. Hamilton· 1 shared

Activity by Year

2021-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

B. D. Bax

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cell BiologyClinical SciencePeer-reviewedDec 15, 2021

The SARS-CoV-2 Spike protein disrupts human cardiac pericytes function through CD147-receptor-mediated signalling: a potential non-infective mechanism of COVID-19 microvascular disease

E. Avolio, M. Carrabba, R. Milligan…·P. Madeddu

This paper shows that SARS-CoV-2 Spike protein causes cardiac pericyte dysfunction through CD147-mediated signaling, without infecting the cells.

DOI 10.1042/cs20210735

humanproteomics

𝕏 PostBluesky

BiochemistrybioRxivAug 19, 2021

Structures of the Human SPAK and OSR1 Conserved C-Terminal (CCT) Domains

K. T. Elvers, M. Lipka-Lloyd, R. C. Trueman…·Y. Mehellou

The paper determines the crystal structures of human SPAK and OSR1 CCT domains and measures their binding affinity to a WNK4 peptide, providing a basis for designing inhibitors targeting SPAK-activation.

DOI 10.1002/cbic.202100441

humanprotein structure

𝕏 PostBluesky

BiophysicsbioRxivPreprintFeb 12, 2021

Tyrosine 121 moves revealing a druggable pocket that couples catalysis to ATP-binding in serine racemase

C. R. Koulouris, S. E. Gardiner, T. K. Harris…·B. D. Bax

The paper identifies a druggable pocket involving Tyr121 that couples catalysis to ATP-binding in serine racemase by analyzing structural changes in closed and open enzyme forms.

DOI 10.1101/2021.02.12.430960

humanstructural biology

𝕏 PostBluesky