J. R. Clark

This study evaluates pro-HlyA and Dual-Hit as vaccine candidates against ExPEC, showing reduced bacterial burden and increased survival in murine models.

This study compares immune landscapes of non-progressing and progressing cutaneous squamous cell carcinomas to identify immune features associated with metastasis.

This study shows that phage resistance in UPEC arises quickly in the urinary environment but comes with fitness costs that reduce bacterial growth and virulence.

This paper investigates phage-antibiotic synergy by analyzing interactions across antibiotic classes and stoichiometries, finding that synergy depends on antibiotic mechanism, phage burst size, and host environment.

This paper describes a phage that targets human glycans to enhance its activity in the gastrointestinal tract by positioning it near bacterial hosts.

This study shows Zika virus replicates in skeletal muscle, contributing to peripheral viral amplification before reaching neural tissues.