J. R. Knudsen

This study shows that microtubule disruption impairs GLUT4 trafficking in skeletal muscle, contributing to insulin resistance.

This study investigates the role of group I p21-activated kinases (PAKs) in contraction-stimulated glucose transport in skeletal muscle, finding that PAK2, but not PAK1, contributes to this process in EDL muscle.

This study investigates the role of PAK1 and PAK2 in insulin-stimulated glucose uptake in mouse skeletal muscle, finding that PAK2, not PAK1, contributes to this process.

This study shows that follistatin overexpression in muscle improves insulin-stimulated glucose uptake and protein synthesis, and that circulating follistatin increases after bariatric surgery, suggesting its role in insulin sensitivity.

This study shows that NOX2 produces cytosolic ROS in skeletal muscle during exercise, which regulates glucose uptake and GLUT4 translocation.

This study shows that NOX2 is necessary for skeletal muscle adaptations to high-intensity interval training, including antioxidant defense and mitochondrial changes.