MND1 and PSMC3IP control PARP inhibitor sensitivity in mitotic cells
A. Zelceski, P. Francica, L. Lingg, M. Mutlu, C. Stok, M. Liptay, J. Alexander, J. S. Baxter, R. Brough, A. Gulati, S. Haider, M. Raghunandan, F. Song, S. Sridhar, J. V. Forment, , C. J. Lord
This study shows that PSMC3IP and MND1 depletion increases PARP inhibitor sensitivity in mitotic cells through impaired D-loop formation and homology-directed repair.
bioRxiv · Aug 24, 2022Cancer Biology