Author

M. Mutlu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Gulati· 1 shared A. Hinniger· 1 shared A. N. J. Tutt· 1 shared A. Zelceski· 1 shared B. Goretzki· 1 shared B. Knapp· 1 shared B. R. Davies· 1 shared C. Fernandez· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

A. Gulati

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Structural basis of dual BACH1 regulation by SCFFBXO22 and SCFFBXL17

B. Goretzki, M. Khoshouei, P. Penner, C. Stephan, D. Argoti, N. Dierlamm, J. M. Rada, S. Kapps, Z. Thiel, M. Mutlu, D. Furkert, C. S. Müller, F. Freuler, S. Haenni, L. Tenaillon, , C. Fernandez

This study elucidates how BACH1 is regulated by SCFFBXO22 and SCFFBXL17 through structural changes in FBXO22 and modifications in BACH1's BTB domain, affecting its ubiquitylation and stability.

bioRxiv · Jun 3, 2024 · PreprintBiophysics

MND1 and PSMC3IP control PARP inhibitor sensitivity in mitotic cells

A. Zelceski, P. Francica, L. Lingg, M. Mutlu, C. Stok, M. Liptay, J. Alexander, J. S. Baxter, R. Brough, A. Gulati, S. Haider, M. Raghunandan, F. Song, S. Sridhar, J. V. Forment, , C. J. Lord

This study shows that PSMC3IP and MND1 depletion increases PARP inhibitor sensitivity in mitotic cells through impaired D-loop formation and homology-directed repair.

bioRxiv · Aug 24, 2022Cancer Biology