Author

J. Schlessinger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

S. An· 2 shared S. Lee· 2 shared A. Anneken· 1 shared A. Etemadi· 1 shared A. Favor· 1 shared A. N. Murray· 1 shared A. Phal· 1 shared B. Coventry· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBioengineering

S. An

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies

N. I. Edman, R. L. Redler, A. Phal, T. Schlichthaerle, S. R. Srivatsan, A. Etemadi, S. An, A. Favor, D. Ehnes, Z. Li, F. Praetorius, M. Gordon, W. Yang, B. Coventry, D. R. Hicks, , D. Baker

This study designs synthetic oligomeric ligands to modulate FGFR signaling and shows their impact on vascular cell fate decisions.

bioRxiv · Mar 14, 2023Bioengineering

Cryo-EM analyses of wild-type and oncogenic KIT mutants reveal structural oncogenic plasticity and a novel Achilles heel for therapeutic intervention

S. G. Krimmer, N. Bertoletti, Y. Suzuki, L. Katic, J. Mohanty, S. Shu, S. Lee, I. Lax, W. Mi, J. Schlessinger

This study uses cryo-EM to analyze wild-type and oncogenic KIT mutants, revealing structural changes and a potential therapeutic target in cancer.

bioRxiv · Sep 8, 2022 · PreprintBiochemistry

Regulation of EGF-stimulated activation of the PI-3K/AKT pathway by exocyst-mediated exocytosis

S. An, A. Anneken, Z. Xi, C. Choi, J. Schlessinger, D. Toomre

This study shows that exocyst-mediated exocytosis regulates PI(3,4,5)P3 levels and AKT activation in response to EGF signaling in epithelial cells.

bioRxiv · Mar 21, 2022Cell Biology