Author

J. Smyth

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:electrophysiology· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

A. J. Lozano· 1 shared A. L. Hanlon· 1 shared C. B. Bain· 1 shared D. R. King· 1 shared D. Yee· 1 shared F. Shewmaker· 1 shared G. A. Blair· 1 shared G. S. Hoeker· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiophysics

A. J. Lozano

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2 papers

Recent·Most cited

EXTRACELLULAR PERINEXAL SEPARATION IS A PRINCIPAL DETERMINANT OF CARDIAC CONDUCTION

W. P. Adams, T. B. Raisch, Y. Zhao, R. Davalos, S. Barrett, D. R. King, C. B. Bain, K. Colucci, G. A. Blair, A. J. Lozano, A. L. Hanlon, R. Veeraraghavan, X. Wan, I. Deschenes, J. Smyth, , S. Poelzing

This study investigates the relationship between cardiac conduction velocity and extracellular space structure, finding a biphasic relationship with perinexal separation, supporting ephaptic coupling over gap junction-based conduction.

bioRxiv · May 25, 2023Biophysics

The oncogenic transcription factor FUS-CHOP can undergo nuclear liquid-liquid phase separation

I. Owen, D. Yee, H. Wyne, T. M. Perdikari, V. Johnson, J. Smyth, R. Kortum, N. L. Fawzi, F. Shewmaker

This study shows the FUS-CHOP fusion protein undergoes nuclear liquid-liquid phase separation, forming condensates at super enhancer sites, suggesting a novel oncogenic mechanism in myxoid liposarcoma.

bioRxiv · Feb 24, 2021Cell Biology