CRISPR Cas13-based tools to track and manipulate endogenous telomeric repeat-containing RNAs in living cells
M. Xu, T. Chigumira, Z. Chen, J. Tones, R. Zhao, K. N. Dahl, D. M. Chenoweth, H. Zhang
This study develops CRISPR Cas13 and Suntag tools to track and manipulate TERRA in live cells, revealing its anomalous diffusion and subcellular localization dynamics.
bioRxiv · Dec 3, 2021 · PreprintCell Biology