Author

D. Chavez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Bioengineering· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Organism:rat· 2

Frequent Co-Authors

R. Lanford· 2 shared A. Antanasijevic· 1 shared A. Bailey· 1 shared A. C. De Jesus· 1 shared A. E. Goodroe· 1 shared A. Mejia-Santana· 1 shared A. Ward· 1 shared B. Guerra· 1 shared

Activity by Year

2018-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

R. Lanford

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Warfarin analogs target disulfide bond-forming enzymes and suggest a residue important for quinone and coumarin binding

D. Chavez, G. N. Amarquaye, A. Mejia-Santana, Dyotima, K. Ryan, L. Zeng, C. Landeta

The paper identifies a conserved residue critical for quinone and coumarin binding in disulfide bond-forming enzymes and demonstrates the potential of warfarin analogs as anticoagulants or antibacterials.

bioRxiv · Feb 18, 2024Microbiology

Rescue of alveolar wall liquid secretion blocks fatal lung injury by influenza-staphylococcal coinfection

S. Tang, A. C. De Jesus, D. Chavez, S. Suthakaran, S. K. L. Moore, R. Rathnasinghe, M. Schotsaert, J. Bhattacharya, J. L. Hook

This study shows that influenza virus inhibits alveolar wall liquid secretion, promoting fatal lung injury from staphylococcal infection, and that restoring this secretion protects against lung damage.

bioRxiv · Jul 7, 2022Physiology

Single-component multilayered self-assembling protein nanoparticles presenting glycan-trimmed uncleaved prefusion optimized envelope trimers as HIV-1 vaccine candidates

Y.-N. Zhang, J. Paynter, A. Antanasijevic, J. D. Allen, M. Eldad, Y.-Z. Lee, J. Copps, M. Newby, L. He, D. Chavez, P. Frost, A. E. Goodroe, J. W. Dutton, R. Lanford, C. Chen, , J. Zhu

Glycan trimming of HIV-1 Env immunogens improves vaccine-induced neutralizing antibody responses in small animals and primates.

bioRxiv · Jul 1, 2022Microbiology

Integrated platform for multi-scale molecular imaging and phenotyping of the human brain

J. Park, J. Wang, W. Guan, L. A. Gjesteby, D. Pollack, L. Kamentsky, N. B. Evans, J. Stirman, X. Gu, C. Zhao, S. Marx, M. E. Kim, S. W. Choi, M. Snyder, D. Chavez, , K. Chung

The paper develops a platform for multi-scale molecular imaging and phenotyping of the human brain, integrating novel tools for tissue processing, imaging, and computational reconstruction.

bioRxiv · Mar 13, 2022 · PreprintBioengineering

Subclinical infection of macaques and baboons with a baboon simartevirus

C. Buechler, M. Semler, D. A. Baker, C. Newman, J. P. Cornish, D. Chavez, B. Guerra, R. Lanford, K. Brasky, J. H. Kuhn, R. F. Johnson, D. H. O'Connor, A. Bailey

This study infects olive baboons and rhesus macaques with SWBV-1, a simartevirus, and finds no disease in either species despite high viral replication and immune responses.

bioRxiv · Aug 22, 2018Microbiology