Cancer BiologybioRxivPreprint
Pan-cancer single cell RNA-seq uncovers recurring programs of cellular heterogeneity
G. S. Kinker, A. C. Greenwald, R. Tal…·I. Tirosh
The paper uses single-cell RNA-seq to analyze cancer cell lines and identifies recurring expression programs of heterogeneity that mirror those in tumors, suggesting intrinsic plasticity contributes to intra-tumoral diversity.