ERK3 Is Involved in Regulating Cardiac Fibroblast Function
P. Sahadevan, D. Dingar, S. A. Nawaito…·B. G. Allen
This study shows ERK3 regulates cardiac fibroblast function by affecting collagen production and motility in response to TGF-β and TAC.
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Primary ORCID profile (0000-0001-5991-4366 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints
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5 papers
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P. Sahadevan, D. Dingar, S. A. Nawaito…·B. G. Allen
This study shows ERK3 regulates cardiac fibroblast function by affecting collagen production and motility in response to TGF-β and TAC.
J. Trepanier, S. A. Nawaito, P. Sahadevan…·B. G. Allen
This study shows MK2 deficiency reduces mortality and alters cytokine levels during the inflammatory phase after myocardial infarction in mice.
M. Ruiz, M. Khairallah, D. Dingar…·B. G. Allen
This study examines the cardiac phenotype of MK2-deficient mice, finding altered autonomic regulation, increased metabolic gene expression, reduced mitochondrial Ca2+-sensitivity, and delayed hypertrophic remodeling in response to pressure overload.
P. Sahadevan, S. A. Nawaito, J. Trepanier…·B. G. Allen
This study investigates MK5 expression, localization, and phosphorylation in cardiac myofibroblasts and myocytes, finding that p38/{beta} mediates T182-MK5 phosphorylation and activation.
G. Coulis, Y. Shi, D. P. Labbe…·B. Boivin
This study shows that PTP1B inactivation disrupts miR-208b-Argonaute 2 interaction, leading to increased THRAP1 expression and thyroid hormone-induced cardiac hypertrophy.