Author

D. P. Labbe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. A. Hamid· 1 shared A. Bergeron· 1 shared A. D. Choudhury· 1 shared A. Ghosh· 1 shared A. Mitrofanova· 1 shared A. S. Kibel· 1 shared A. Sharma· 1 shared A. Sowalsky· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCancer Biology

A. A. Hamid

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

SOCS3-mediated activation of p53-p21-NRF2 axis and cellular adaptation to oxidative stress in SOCS1-deficient hepatocellular carcinoma

M. M. Khan, N. Boufaied, M. Yeganeh, A. Ghosh, R. Kandhi, R. Bagheri, S. Petkiewicz, A. Sharma, A. Yoshimura, G. Ferbeyre, D. P. Labbe, S. Ramanathan, S. Ilangumaran

The paper shows that SOCS1 deficiency leads to increased SOCS3 expression, which activates the p53-p21-NRF2 axis, reducing oxidative stress and HCC progression.

bioRxiv · Oct 21, 2021 · PreprintCancer Biology

Protein Tyrosine Phosphatase 1B Regulates MicroRNA-208b-Argonaute 2 Association and Thyroid Hormone Responsiveness in Cardiac Hypertrophy

G. Coulis, Y. Shi, D. P. Labbe, A. Bergeron, F. Sahmi, V. Vinette, G. Karsenty, B. G. Allen, M. Tremblay, J.-C. Tardif, B. Boivin

This study shows that PTP1B inactivation disrupts miR-208b-Argonaute 2 interaction, leading to increased THRAP1 expression and thyroid hormone-induced cardiac hypertrophy.

bioRxiv · Sep 10, 2019 · PreprintCell Biology

Targeting EZH2 Increases Therapeutic Efficacy of Check-Point Blockade in Models of Prostate Cancer

A. V. Sheahan, K. L. Morel, D. L. Burkhart, S. C. Baca, D. P. Labbe, K. Roehle, M. Heckler, C. Calagua, H. Ye, P. Galbo, S. Panja, A. Mitrofanova, A. A. Hamid, A. S. Kibel, A. D. Choudhury, , L. Ellis

This study shows that inhibiting EZH2 enhances the effectiveness of PD-1 checkpoint inhibitors in prostate cancer by increasing PD-L1 expression and immune cell infiltration.

bioRxiv · Aug 8, 2019 · PreprintCancer Biology