B. G. Allen

This study shows ERK3 regulates cardiac fibroblast function by affecting collagen production and motility in response to TGF-β and TAC.

This study shows auranofin inhibits TrxR in SCLC and NET cells, sensitizes them to sorafenib, and extends survival in xenograft models without toxicity.

This study shows MK2 deficiency reduces mortality and alters cytokine levels during the inflammatory phase after myocardial infarction in mice.

The paper shows that reducing mitochondrial pyruvate carrier activity in kidney tubular cells protects against acute kidney injury by enhancing redox defenses and survival.

This study examines the cardiac phenotype of MK2-deficient mice, finding altered autonomic regulation, increased metabolic gene expression, reduced mitochondrial Ca2+-sensitivity, and delayed hypertrophic remodeling in response to pressure overload.

The paper synthesizes and characterizes pepducins from the urotensin II receptor, showing they act as biased allosteric modulators with specific signaling effects.

This study investigates MK5 expression, localization, and phosphorylation in cardiac myofibroblasts and myocytes, finding that p38/{beta} mediates T182-MK5 phosphorylation and activation.

This study shows that PTP1B inactivation disrupts miR-208b-Argonaute 2 interaction, leading to increased THRAP1 expression and thyroid hormone-induced cardiac hypertrophy.