Hepatic Macrophage Migration Inhibitory Factor Promotes Pancreatic Cancer Liver Metastasis in NAFLD
Q. YU, H. Song, L. Zhu, X.-y. Shi, H.-z. Wang, Y.-l. Wang, R.-n. Gong, J.-f. Cui, X.-n. Yang, J.-g. Wang, Y. Liang, Y. Chen, X.-w. Dong, G.-t. Lu, C. Li, , H. Ren
This study shows that hepatic MIF promotes PDAC liver metastasis in NAFLD by enhancing cancer stemness and immune suppression through the MIF-CD44 axis.
bioRxiv · Jun 2, 2024 · PreprintCancer Biology