Universal and naked-eye gene detection platform based on CRISPR/Cas12a/13a system
C.-Q. Yuan, T. Tian, J. Sun, M.-L. Hu, X.-S. Wang, E.-H. Xiong, M. Cheng, Y.-J. Bao, W. Lin, J.-M. Jiang, C.-W. Yang, Q. Chen, H. Wang, X.-R. Wang, X.-B. Deng, , X. Zhou
This paper develops a CRISPR-based colorimetric gene detection platform using AuNPs that enables naked-eye detection of DNA and RNA targets with high sensitivity and universality.
bioRxiv · May 7, 2019Bioengineering