Author

J.-P. Issa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

J. Jelinek· 2 shared A. Bellacosa· 1 shared C. Scher· 1 shared E. Koltsova· 1 shared E. Nicolas· 1 shared G. Scher· 1 shared I. Peshkova· 1 shared J. Ingram· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

J. Jelinek

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2 papers

Recent·Most cited

Ultraviolet radiation modulates DNA methylation in melanocytes

S. Preston-Alp, J. Jelinek, J.-P. Issa, M. R. Zaidi

This study shows UVR induces DNA methylation and transcriptome changes in melanocytes, affecting CpG sites and signaling pathways, with potential implications for melanoma susceptibility.

bioRxiv · Oct 14, 2021 · PreprintCancer Biology

TET1 and TDG suppress intestinal tumorigenesis by down regulating the inflammatory and immune response pathways

R. Tricarico, J. Madzo, G. Scher, S. Maegawa, J. Jelinek, C. Scher, W.-C. Chang, E. Nicolas, Y. Zhou, M. Slifker, K. Devarajan, K. Q. Cai, P. Nakajima, J. Xu, P. Mancuso, , A. Bellacosa

This study shows that TET1 and TDG reduce intestinal tumor formation by suppressing inflammatory and immune response pathways through DNA demethylation.

bioRxiv · Jun 21, 2019 · PreprintCancer Biology