Cancer BiologybioRxiv
Cooperation between oncogenic Ras and p53 stimulates JAK/STAT non-cell autonomously to promote Ras tumor radioresistance
Y.-L. Dong, G. Valdka, J.-Y. J. Lu…·C. Y. Chabu
The paper shows that oncogenic Ras and p53 cooperation activates JAK/STAT non-cell autonomously in the tumor microenvironment, promoting radioresistance and tumor recurrence.
DOI 10.1038/s42003-021-01898-5