BiophysicsNature CommunicationsPeer-reviewed
Nucleosome unwrapping and PARP1 allostery drive affinities for chromatin and DNA breaks
Matthew A. Schaich, Tyler Weaver, Jennifer A Rakowski…·Bennett Van Houten
This study investigates how PARP1 binds to DNA breaks and chromatin, revealing that nucleosome unwrapping and allostery influence its affinity and binding dynamics.
7 citations