Molecular BiologybioRxivPreprint
The KAT2 Acetyltransferase PCAF-1 Couples Stress-Responsive Transcription to Proteostasis and Longevity
Avinash Sharma, Khairun Nisaa, Lina Blanco-Rodriguez…·Carlos Giovanni Silva-Garcia
This study shows increasing PCAF-1 in C. elegans extends lifespan, preserves healthspan, and enhances stress responses by reprogramming transcription and improving proteostasis.
DOI 10.64898/2026.11.10.765553