Author

Khairun Nisaa

Brown UniversityORCID 0000-0001-7675-3007Unclaimed ORCID profile · follow to get notified of new preprints

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Organism:C. elegans· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Carlos Giovanni Silva-GarciaiD· 2 shared Erica DinneeniD· 2 shared Avinash SharmaiD· 1 shared Avinash SharmaiD· 1 shared Jeremy Tachiki· 1 shared Lina Blanco-RodrigueziD· 1 shared Mai Huong ToiD· 1 shared Purbasha Dasgupta· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 20 mutual co-author links

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2 shared papersMolecular Biology

Carlos Giovanni Silva-GarciaORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintNov 12, 2026

The KAT2 Acetyltransferase PCAF-1 Couples Stress-Responsive Transcription to Proteostasis and Longevity

Avinash Sharma, Khairun Nisaa, Lina Blanco-Rodriguez…·Carlos Giovanni Silva-Garcia

This study shows increasing PCAF-1 in C. elegans extends lifespan, preserves healthspan, and enhances stress responses by reprogramming transcription and improving proteostasis.

DOI 10.64898/2026.11.10.765553

C. elegansgenetic perturbation / CRISPR

𝕏 PostBluesky

GeneticsG3 Genes Genomes GeneticsPeer-reviewedSep 19, 2025

Universal Single Copy Knock-In System in Caenorhabditis elegans: One Plasmid to Target All Chromosomes

Erica Dinneen, Purbasha Dasgupta, Avinash Sharma…·Carlos G. Silva-García

The paper introduces a universal single-copy knock-in system for C. elegans that allows transgene insertion at specific loci using CRISPR/Cas9.

DOI 10.1093/g3journal/jkaf220

C. elegansCRISPR screen

𝕏 PostBluesky