ImmunologybioRxivPreprint
The N-end rule E3 ligase UBR2 activates Nlrp1b inflammasomes
Hao Xu, Jianjin Shi, Zhenxiao Yang…·Na Dong
This study identifies UBR2 as an essential E3 ligase for LF-induced Nlrp1b inflammasome activation through degradation of Nlrp1b's N-terminal fragment.
DOI 10.1101/429225