Author
Baylor College of Medicine
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
8 papers
Recent·Most cited
Yangfang Xiong, Jiwu Ren, Xiaoxu Wei, Xiaoyu Li, Jiayi Li, Wensheng Wei
This paper introduces PDLMs, protein-DNA language models that jointly represent protein and DNA sequences to predict and engineer DNA recognition specificity.
bioRxiv · Nov 6, 2026 · PreprintBioinformatics
Armando M. Marrufo, Chris H. Wendt, Eric Garshick, Vincent S. Fan, Raúl San Jośe Estépar, Lizhen Song, Jiayi Li, Sarvika Periyapalayam Murali, Ivan M. Marrufo, Maxwell Stewart, Demerise Johnston, David Brian Corry, Tianshi David Wu, Farrah Kheradmand
The paper identifies a T2/T17 immune signature in individuals with persistent respiratory symptoms linked to airborne pollutant exposure and small-airway dysfunction.
bioRxiv · Aug 21, 2026 · PreprintImmunology
Yutaro Tanaka, James J. Morrow, Salvador Casaní-Galdón, Erica Maria Pimenta, Jiayi Li, Byron Butaney, Chadi A. El Farran, Julie Karam, Joshua P. D’Antonio, Kevin Bi, Laura Valderrábano, Sabrina Yvonne Camp, Yun Jee Kang, Shreya Johri, Lester Heredia Gopar, , Riaz Gillani
This study identifies a loss of osteoblastic lineage fidelity in metastatic osteosarcoma through single-nucleus RNA sequencing, linking it to disease progression and potential therapeutic targets.
bioRxiv · Jun 12, 2026 · PreprintCancer Biology
Bohan Zhu, Anurupa Ghosh, Zhe Wang, Zhicong Liao, Michael Gyasi Appiah, Jiayi Li, Mimi Zhang, Federico Di Tullio, Agata Kurowski, John F. Fullard, Elvin Wagenblast, Martin J. Walsh, Alison Goate, Panos Roussos, Ka Lung Cheung, , Sai Ma
The paper introduces ME-seq, a technology that profiles DNA methylation, gene expression, and chromatin accessibility in single nuclei, revealing early microglial priming in Alzheimer's disease.
bioRxiv · Feb 2, 2026 · PreprintGenomics
Taku Yamamoto, Keitaro Hase, Joseph B. Lin, Shinobu Yamaguchi, Norihiko Misawa, Jiayi Li, Kenta Kato, Ryo Terao, Brian S. Sohn, Daniel Du, Mitsukuni Yoshida, Charles W. Pfeifer, Tae Jun Lee, Jason J. Colasanti, Andrea C. Santeford, , Rajendra S. Apte
This study shows that aging impairs macrophage-induced regulatory T cells in mice, leading to chronic uveitis by linking immunosenescence to persistent inflammation.
bioRxiv · Jan 20, 2026 · PreprintImmunology
Jiayi Li, Bingchen Chen, Yun Zhang, Yang Xu, Lei Wang, Jinhui Wang
The paper investigates how psychological stress induces fear and anxiety by altering neuronal infrastructures in sensory and prefrontal cortices, with KiF1a-mediated transport playing a critical role.
bioRxiv · Jul 29, 2025 · PreprintNeuroscience
Maolei Gong, Jiayi Li, Yijun Liu, Matheus Vernet Machado Bressan Wilke, Qian Li, Haoran Liu, Liang Chen, Joel A. Morales‐Rosado, Ana S.A. Cohen, Susan Starling Hughes, Bonnie R. Sullivan, Valerie Waddell, Marie‐José H. van den Boogaard, Richard H. van Jaarsveld, Ellen van Binsbergen, , Xiaoli Chen
This study identifies MARK2 variants as a cause of autism spectrum disorder by showing they disrupt the WNT/β-catenin signaling pathway and impair neural development.
medRxiv · Apr 24, 2024 · PreprintGenetic & Genomic Medicine
Alexandra J. Ng, Lindsay K. Vincelette, Jiayi Li, Bridget H. Brady, John P. Christianson
This study shows that serotonin in the dorsal raphe nucleus and insular 5-HT2C receptors modulate social responses to stressed rats, with effects observed in both males and females.
bioRxiv · Feb 18, 2023 · PreprintNeuroscience