Jie Yang

SCN- induces prestin contraction through reduced intermonomer angles and a modified transporter like movement of each monomer.

The paper investigates how SCN- induces prestin contraction through structural changes in its dimers and monomers, associated with altered intermonomer angles and beta sheet loss.

Purkinje cell intrinsic activity shapes cerebellar development and function

This study shows that Purkinje cell intrinsic activity before synaptic maturation is critical for dendrite growth, connectivity, and cerebellar function, with early disruptions causing severe morphological and functional defects.

Investigating the Mitochondria-Related Mechanisms of Ligustri Lucidi Fructus in Treating Diabetic Nephropathy: A Combined Approach of Network Pharmacology, Transcriptomics, and Experimental Validation

Multi-modal profiling identifies CD4+CXCR5+PD-1- Tfh cells as prognostic and predictive biomarkers for response to R-CHOP therapy in human DLBCL

The paper identifies CD4+CXCR5+PD-1- Tfh cells as prognostic and predictive biomarkers for R-CHOP therapy response in DLBCL using single-cell RNA sequencing and multiplex IHC.

Mixed selectivity coding of content-temporal detail by dorsomedial posterior parietal neurons

The paper identifies mixed selectivity neural codes in macaque dorsomedial parietal cortex for processing naturalistic video content and temporal information.

TET1 Modulates H4K16 Acetylation by Interacting with hMOF to Regulate Expression of DNA Repair Genes and Oncogenic Transformation