Author

Jin-Hui Ding

Peking University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:cryo-EM· 2 Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Jiale WangiD· 3 shared Jin‐Peng SuniD· 3 shared Renjie ChaiiD· 2 shared Shuhua ZhouiD· 2 shared Weifeng ZhangiD· 2 shared Xiao YuiD· 2 shared Ao YangiD· 1 shared Chanjuan XuiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

Jiale WangORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structural Basis of Asymmetric Class C GPCR activation and distinct Gq coupling induced by force stimulation

Jin-Hui Ding, Jiale Wang, Weifeng Zhang, Shuhua Zhou, Chanjuan Xu, Wei Ding, Wan-Ping Zhuang, Qiyue Zhang, Chao Zhang, Jie Cheng, Yunan Sun, Yu Sun, Renjie Chai, Xiao Yu, Zhao Yang, , Jin‐Peng Sun

This paper reveals how mechanical force activates mGlu2 through a unique cis mechanism and induces distinct Gq coupling, providing structural insights and a chemical toolset for modulating mechanosensitive GPCRs.

bioRxiv · Dec 10, 2025 · PreprintCell Biology

A Mechanosensitive GPCR at vestibular kinocilium is required for normal balance

Shuhua Zhou, Xiao-Hui Wang, Qi-Yue Zhang, Jianing Xu, Jiale Wang, Weifeng Zhang, Jin-Hui Ding, Ming-Wei Wang, Yaqi Wang, Peng-Han, Renjie Chai, Wenwen Liu, Xiao Yu, Yu Sun, Yang Zhao, Jin‐Peng Sun

This study identifies mGlu2 as a mechanosensitive GPCR in vestibular hair cells essential for balance, distinct from its role in hearing.

bioRxiv · Dec 8, 2025 · PreprintCell Biology

Structural insights into cholesterol sensing by the LYCHOS-mTORC1 pathway

Shang Juan Yu, Jin-hui Ding, Jiale Wang, Weize Wang, Peng Zuo, Ao Yang, Zonglin Dai, Yuxin Yin, Jin‐Peng Sun, Ling Liang

This study reveals the structural mechanism of cholesterol sensing by LYCHOS, showing how cholesterol binding modulates its interaction with GATOR1 to activate mTORC1.

Nature Communications · Jul 23, 2025Peer-reviewedBiochemistry