BioengineeringbioRxivPreprint
Extracellular Vesicle-Mediated Delivery of HIF1a Reprograms Macrophages for resolutive response in Sepsis
Yeji Lee, Jiyoung Goo, Seongeon Cho…·In-San Kim
This study delivers HIF1 via extracellular vesicles to reprogram hepatic macrophages, promoting pro-efferocytic and pro-survival macrophage subsets to enhance sepsis resolution.
DOI 10.1101/2024.08.29.608900