NeuroscienceFrontiers in NeurosciencePeer-reviewed
Changes in perineuronal net and parvalbumin expression in the orbitofrontal cortex of male Wistar rats following repeated fentanyl administration
Mariana I.H. Dejeux, Sarah Jewanee, Samuel Moutos…·Jacques D. Nguyen
This study examines how repeated fentanyl administration affects perineuronal nets and parvalbumin expression in rat orbitofrontal cortex, showing changes in antinociceptive tolerance and PNN/PV correlations.
DOI 10.3389/fnins.2026.1821692