BiochemistrybioRxivPreprint
ssDNA hand-off from RPA to Polθ drives microhomology-mediated end-joining
Martha Longley, Hyunjee Lee, Owen Eby…·Johannes Walter
The paper reveals that RPA activates TMEJ by facilitating ssDNA hand-off to Polθ, which initiates microhomology search for DNA repair.
DOI 10.64898/2026.10.26.762034