Author

K. A. Gwin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. D. Badley· 1 shared A. Wu· 1 shared G. Ruan· 1 shared H. Dong· 1 shared J. P. Abeykoon· 1 shared J. Paludo· 1 shared K. E. Nowakowski· 1 shared M. K. Manske· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

A. D. Badley

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1 paper

Recent·Most cited

ImmunologybioRxivDec 2, 2021

Secreted ORF8 is a pathogenic cause of severe Covid-19 and potentially targetable with select NLRP3 inhibitors

X. Wu, M. K. Manske, G. Ruan…·T. E. Witzig

This study identifies ORF8 as a secreted glycoprotein that drives severe COVID-19 through NLRP3 inflammasome activation and shows it is inhibited by MCC950.

DOI 10.1016/j.isci.2023.106929

humanproteomics

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