Author

K. A. Smith

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. Buchberger· 1 shared A. Hawkins-Daarud· 1 shared A. Rahimi Kahmini· 1 shared A. Stokes· 1 shared A. T. Papenfuss· 1 shared A. W. Hudson· 1 shared B. M. Hogan· 1 shared B. Morris· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. Buchberger

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Assessing a Role for Sarcospan in Immune Function

I. C. Valera, A. Rahimi Kahmini, K. A. Smith, R. Q. Crawford, M. S. Parvatiyar

This study investigates the role of sarcospan in immune function by analyzing its expression in immune cells and assessing its impact on B cell development and effector functions in SSPN-deficient mice.

bioRxiv · Mar 31, 2024 · PreprintImmunology

Elys deficiency constrains Kras-driven tumour burden by amplifying oncogenic stress

K. J. Morgan, K. Doggett, F.-S. Geng, L. Whitehead, K. A. Smith, B. M. Hogan, C. Simons, G. J. Baillie, R. Molania, A. T. Papenfuss, T. E. Hall, E. A. Ober, D. Y. R. Stainier, Z. Gong, J. K. Heath

The paper shows that reducing Elys function in a zebrafish model of Kras-driven liver cancer reduces tumour burden by inducing DNA damage and cell death.

bioRxiv · Aug 25, 2021Cancer Biology

The roseoloviruses downregulate the protein tyrosine phosphatase PTPRC(CD45)

M. L. Whyte, K. A. Smith, A. Buchberger, L. Berg Luecke, L. Handayani Tjan, Y. Mori, R. Gundry, A. W. Hudson

This study identifies that HHV6A and HHV7 downregulate CD45 on T cells, impairing immune signaling and potentially promoting viral latency.

bioRxiv · Sep 29, 2020Microbiology

Identifying the spatial and temporal dynamics of molecularly-distinct glioblastoma sub-populations

B. Morris, L. Curtin, A. Hawkins-Daarud, M. E. Hubbard, R. Rahman, S. J. Smith, D. Auer, N. L. Tran, L. S. Hu, J. M. Eschbacher, K. A. Smith, A. Stokes, K. R. Swanson, M. R. Owen

The paper uses biopsy data and a mechanistic model to study interactions between EGFR and PDGFRA amplified sub-populations in glioblastomas.

bioRxiv · Apr 8, 2020Cancer Biology