Cancer BiologybioRxiv
Elys deficiency constrains Kras-driven tumour burden by amplifying oncogenic stress
K. J. Morgan, K. Doggett, F.-S. Geng…·J. K. Heath
The paper shows that reducing Elys function in a zebrafish model of Kras-driven liver cancer reduces tumour burden by inducing DNA damage and cell death.
DOI 10.7554/elife.73407