Author

K. A. Wani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 4 Research Focus:host-pathogen & immune response· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Assay:proteomics· 2 Research Focus:development & morphogenesis· 1 Organism:E. coli· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

J. E. Irazoqui· 2 shared N. D. Peterson· 2 shared R. Pukkila-Worley· 2 shared A. Ghazi· 1 shared A. L. Page· 1 shared A. Page· 1 shared A. Wood· 1 shared C. E. Tocheny· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersPhysiology

J. E. Irazoqui

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

ImmunologybioRxivPreprintDec 4, 2023

Activation of intestinal immunity by pathogen effector-triggered aggregation of lysosomal TIR-1/SARM1

S. Tse-Kang, K. A. Wani, N. D. Peterson…·R. Pukkila-Worley

The paper identifies lysosomal TIR-1/SARM1 as a sensor for oxidative stress induced by pathogenic bacteria, activating intestinal immunity in C. elegans.

DOI 10.1101/2023.12.04.569946

C. elegansproteomics

𝕏 PostBluesky

PhysiologybioRxivPreprintNov 19, 2023

Glucose-fed microbiota alters intestinal epithelium and increases susceptibility to bacterial pathogens

S. F. Kingsley, Y. Seo, A. Wood…·H. A. Tissenbaum

This study shows that a glucose-fed microbiota in C. elegans reduces lifespan and healthspan, increases intestinal permeability, and raises susceptibility to bacterial pathogens.

DOI 10.1101/2023.11.19.567723

C. elegansE. coli

𝕏 PostBluesky

ImmunologybioRxivPreprintAug 10, 2023

Transcriptional suppression of sphingolipid catabolism controls pathogen resistance in C. elegans

M. A. Nasrallah, N. D. Peterson, J. E. Salisbury…·R. Pukkila-Worley

The paper identifies NHR-66 as a transcriptional repressor that suppresses sphingolipid catabolism to enhance pathogen resistance in C. elegans.

DOI 10.1101/2023.08.10.552843

C. elegansbulk RNA-seq

𝕏 PostBluesky

MicrobiologybioRxivSep 3, 2020

NHR-49/PPAR-α and HLH-30/TFEB promote C. elegans host defense via a flavin-containing monooxygenase

K. A. Wani, D. Goswamy, S. Taubert…·J. E. Irazoqui

This study identifies NHR-49/PPAR-α and HLH-30/TFEB as regulators of an infection-specific host response in C. elegans, revealing FMOs as innate immunity effectors.

DOI 10.7554/elife.62775

C. elegansbulk RNA-seq

𝕏 PostBluesky