K. Aquilano

This study shows that frataxin deficiency in microglia shifts metabolism to glucose catabolism, causing inflammation, which is mitigated by butyrate treatment.

This study shows that a low-protein/high-carbohydrate diet activates AMPK-dependent thermogenic pathways in subcutaneous adipose tissue, enhancing energy dissipation and metabolic health.

This study shows that frataxin deficiency in mice leads to BAT dysfunction, including lipid accumulation and impaired thermogenesis, contributing to metabolic complications in Friedreichs ataxia.