BiochemistrybioRxiv
The molecular basis of ubiquitin-specific protease 8 autoinhibition by the WW-like domain
K. Kakihara, K. Asamizu, K. Moritsugu…·T. Fukushima
This study identifies an autoinhibitory WW-like domain in USP8 that regulates its enzyme activity and links its release to Cushings disease.
DOI 10.1038/s42003-021-02802-x