K. Moritsugu

This study identifies the CNH domain of NRK as a key mediator of cell death by localizing to the plasma membrane via phospholipid binding.

This study investigates the binding and unbinding pathways of an eight-residue peptide to SARS-CoV-2 3CL protease using weighted ensemble simulations, revealing the sequential formation of hydrogen bonds during the binding process.

The paper analyzes the structural dynamics of SARS-CoV-2 and SARS-CoV 3CLpro using crystal structures to understand allosteric regulation and ligand binding effects.

This study identifies an autoinhibitory WW-like domain in USP8 that regulates its enzyme activity and links its release to Cushings disease.

This paper introduces a new molecular dynamics method that enhances sampling without iteration or replica systems by dynamically coupling temperature and energy variables.

This study calculates the minimum free energy pathway of functional rotation in AcrB, linking it to proton translocation and drug transport at the atomic level.