A helminth chitinase structurally similar to mammalian chitinase displays immunomodulatory properties
F. Ebner, K. Balster, K. Janek, A. Niewienda, P. H. Malecki, M. S. Weiss, T. E. Sutherland, A. Heuser, A. A. Kühl, J. Zentek, A. Hofmann, S. Hartmann
This paper identifies a helminth chitinase with immunomodulatory effects in a murine allergic model, showing structural similarity to mammalian chitinase and inducing cross-reactive antibodies.
bioRxiv · May 17, 2019 · PreprintImmunology