Prdm16 mutation determines sex-specific cardiac metabolism and identifies two novel cardiac metabolic regulators
J. Kuhnisch, S. Theisen, J. Dartsch, R. Fritsche-Guenther, M. Kirchner, B. Obermayer, A. Bauer, A.-K. Kahlert, M. Rothe, D. Beule, A. Heuser, P. Mertins, J. A. Kirwan, N. Berndt, C. A. MacRae, , S. Klaassen
This study investigates monoallelic Prdm16 mutation in mice, revealing sex-specific cardiac metabolic dysregulation and identifying Pyroxd2 and Pbxip1 as novel metabolic regulators.
bioRxiv · Jan 10, 2023 · PreprintPathology