Author

K. Janek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. A. Kuehl· 1 shared A. A. Kühl· 1 shared A. Heuser· 1 shared A. Hofmann· 1 shared A. Niewienda· 1 shared A. Petersen· 1 shared B. Sawitzki· 1 shared C. Appelt· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. A. Kuehl

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Author profile →

2 papers

Recent·Most cited

TCAIM controls effector T cell generation by preventing Mitochondria-Endoplasmic Reticulum Contact Site-initiated Cholesterol Biosynthesis

C. Iwert, J. Stein, C. Appelt, K. Vogt, R. J. Rainer, K. Tummler, K. Muehle, K. Stanko, J. Schumann, D. Uebe, K. Juerchott, J. Lisec, K. Janek, C. Gille, K. Textoris-Taube, , B. Sawitzki

This study shows TCAIM prevents effector T cell differentiation by inhibiting mitochondria-ER contact sites that drive cholesterol biosynthesis and HIF1 activation.

bioRxiv · Apr 20, 2021 · PreprintImmunology

A helminth chitinase structurally similar to mammalian chitinase displays immunomodulatory properties

F. Ebner, K. Balster, K. Janek, A. Niewienda, P. H. Malecki, M. S. Weiss, T. E. Sutherland, A. Heuser, A. A. Kühl, J. Zentek, A. Hofmann, S. Hartmann

This paper identifies a helminth chitinase with immunomodulatory effects in a murine allergic model, showing structural similarity to mammalian chitinase and inducing cross-reactive antibodies.

bioRxiv · May 17, 2019 · PreprintImmunology