Author

A. Hofmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Ecology· 1 Immunology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:proteomics· 3 Organism:Arabidopsis· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Research Focus:ecology & biodiversity· 1

Frequent Co-Authors

A. A. Kühl· 1 shared A. Heuser· 1 shared A. Niewienda· 1 shared A. Vulpetti· 1 shared B. Bauer-Probst· 1 shared B. Chung· 1 shared B. Dubreuil· 1 shared B. Pinch· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperImmunology

A. A. Kühl

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Author profile →

5 papers

Recent·Most cited

Reinstating targeted protein degradation with DCAF1 PROTACs in CRBN PROTAC resistant settings

M. Schroeder, M. Renatus, X. Liang, F. Meili, S. Ferrand, F. Gauter, X. Li, F. Sigoillot, S. Gleim, M.-T. Stachyra, J. Thomas, M. Schirle, T. Zoller, D. Begue, P. Lefeuvre, , C. R. Thoma

This study develops DCAF1-based PROTACs to overcome CRBN resistance in targeted protein degradation, demonstrating effective degradation of BTK in CRBN-resistant cells.

bioRxiv · Apr 9, 2023 · PreprintBiochemistry

Desalination and temperature increase will shift seasonal grazing patterns of invasive Gammarus tigrinus on charophytes

M. Berthold, C. Porsche, A. Hofmann, P. Nowak

This study examines how temperature and salinity changes affect grazing by invasive Gammarus tigrinus on charophytes, predicting shifts in grazing patterns under future climate conditions.

bioRxiv · Mar 1, 2021Ecology

Proteomic analysis reveals the recruitment of intrinsically disordered regions to stress granules

M. Zhu, E. R. Kuechler, J. Zhang, O. Matalon, B. Dubreuil, A. Hofmann, C. J. R. Loewen, E. Levy, J. Gsponer, T. Mayor

The paper identifies heat-regulated yeast proteins that localize to stress granules, showing intrinsically disordered regions (IDRs) are sufficient for SG recruitment and play a critical role in heat-stress response.

bioRxiv · Sep 5, 2019Cell Biology

A peptide pair coordinates regular ovule initiation patterns with seed number and fruit size

N. Kawamoto, D. Pino del Carpio, A. Hofmann, Y. Mizuta, K. Daisuke, T. Higashiyama, N. Uchida, K. U. Torii, L. Colombo, G. Groth, R. Simon

This study identifies two peptides, EPFL2 and EPFL9, and their receptors that coordinate ovule spacing, seed number, and fruit size in Arabidopsis thaliana through auxin feedback.

bioRxiv · Aug 15, 2019Plant Biology

A helminth chitinase structurally similar to mammalian chitinase displays immunomodulatory properties

F. Ebner, K. Balster, K. Janek, A. Niewienda, P. H. Malecki, M. S. Weiss, T. E. Sutherland, A. Heuser, A. A. Kühl, J. Zentek, A. Hofmann, S. Hartmann

This paper identifies a helminth chitinase with immunomodulatory effects in a murine allergic model, showing structural similarity to mammalian chitinase and inducing cross-reactive antibodies.

bioRxiv · May 17, 2019 · PreprintImmunology