Patient-derived xenograft culture-transplant system for investigation of human breast cancer metastasis
D. Ma, G. A. Hernandez, A. E. Y. T. Lefebvre, H. Alshetaiwi, K. Blake, K. R. Dave, M. Rauf, J. W. Williams, R. T. Davis, K. T. Evans, M. Y. G. Masoud, R. Lee, R. A. Edwards, M. A. Digman, K. Kessenbrock, D. A. Lawson
This paper develops a 3D tumor sphere culture-transplant system to study human breast cancer metastasis using patient-derived xenografts and validates its utility for functional metastasis assays.
bioRxiv · Jun 25, 2020 · PreprintCancer Biology