R. A. Edwards

This paper describes a multi-epitope vaccine that provides cross-protection against multiple SARS-CoV-2 variants by inducing functional T cell responses.

The paper characterizes active temperate gut phages from bacterial isolates, finding most are inactive and their induction is complex and context-dependent.

This study shows RAGE-Ig reduces viral replication and inflammation in multiple SARS-CoV-2 variants using animal models and human cells.

This study examines the global biogeography of butyrate-producing bacteria and identifies key environmental factors influencing their distribution.

This study shows SARS-CoV-2 infects neurons in the CNS of K18-hACE2 mice, with microglia not restricting viral replication but contributing to inflammation.

This study examines immune changes in pregnant women with mild SARS-CoV-2 infection, finding altered immune responses in blood and decidua that may impact fetal development.

This paper identifies an antibody epitope and a risk score to predict severe COVID-19 outcomes with high specificity.

The paper identifies conserved B-cell and T-cell epitopes across multiple Coronaviruses to inform the development of a pan-Coronavirus vaccine.

This paper develops a 3D tumor sphere culture-transplant system to study human breast cancer metastasis using patient-derived xenografts and validates its utility for functional metastasis assays.

This study shows that reducing Wnt signaling in colon cancer cells increases their invasiveness and identifies gene markers predictive of poor patient outcomes.

The paper evaluates taxonomy methods for bacteriophages using Spounavirinae as a case study, finding they should be divided into at least five subfamilies.